
Breast cancer is usually considered to have a strong genetic influence. But up till date, nearly 25 % of the genes were likely to cause inherited breast cancer have been discovered.
The new genes are FGFR2, TNRC9,MAP3K1 and LSP1 are thought to account for another 4%.
The report mentioned that — to find for few of the many other genes believed to make slight differences to a females breast cancer chances, Easton and his team members compared the genomes of at least 4,400 females who have breast cancer with those of about 4,300 who did not have the disease.
The researchers discovered thirty differences in single DNA bases that seemed to be associated with breast cancer. These were then compared in approximately 20,000 females with breast cancer and in a similar number of controls.
3 of the newly identified genes are found to be involved in controlling the cell development. Fibroblast growth factor receptor 2, or FGFR2 is the gene with the strongest association.
Easton and his team discovered that-females who have 2 copies of the high-risk version of this gene nearly 16% of the population have a 60% higher risk of developing breast cancer than do those females who have no copies of the gene.
The science journal Nature reported this on Sunday.
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